Identification of a novel nitroflavone-based scaffold for designing mutant-selective EGFR tyrosine kinase inhibitors targeting T790M and C797S resistance in advanced NSCLC

Cristina, M; Emiliano, L; Leonardo, S; Giulia, S; Roberta, G; Adolfo, A; Marta, SS; Paola, S; Samuele, R; Pierluigi, S; Massimo, M; Giovanna, M

Giovanna, M (通讯作者)，Marche Polytech Univ, Dept Life & Environm Sci, I-60131 Ancona, Italy.

BIOORGANIC CHEMISTRY, 2022; 129 ():

Abstract

The inhibition of the Epidermal Growth Factor (EGFR) represents one of the most promising strategies in non-small cell lung cancer (NSCLC) therapy. Th......

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