A CD47-associated super-enhancer links pro-inflammatory signalling to CD47 upregulation in breast cancer

Betancur, PA; Abraham, BJ; Yiu, YY; Willingham, SB; Khameneh, F; Zarnegar, M; Kuo, AH; McKenna, K; Kojima, Y; Leeper, NJ; Ho, P; Gip, P; Swigut, T; Sherwood, RI; Clarke, MF; Somlo, G; Young, RA; Weissman, IL

Weissman, IL (reprint author), Stanford Univ, Sch Med, Inst Stem Cell Biol & Regenerat Med, Stanford, CA 94305 USA.; Weissman, IL (reprint author), Stanford Univ, Sch Med, Ludwig Ctr Canc Stem Cell Res & Med, Stanford, CA 94305 USA.; Young, RA (reprint au

NATURE COMMUNICATIONS, 2017; 8 ( ):

Abstract

CD47 is a cell surface molecule that inhibits phagocytosis of cells that express it by binding to its receptor, SIRP alpha, on macrophages and other i......

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