BRAF mutant colorectal cancer: ErbB2 expression levels as predictive factor for the response to combined BRAF/ErbB inhibitors

Miele, E; Abballe, L; Spinelli, GP; Besharat, ZM; Catanzaro, G; Chiacchiarini, M; Vacca, A; Po, AN; Capalbo, C; Ferretti, E

Miele, E (corresponding author), Sapienza Univ Rome, Dept Mol Med, Viale Regina Elena 291, I-00161 Rome, Italy.; Miele, E (corresponding author), Ist Italiano Tecnol, Ctr Life NanoSci Sapienza, I-00161 Rome, Italy.; Miele, E (corresponding author), Bambino Gesu Pediat Hosp, Dept Oncohaematol Cellular & Genet Therapy Pediat, Piazza S Onofrio 4, I-00165 Rome, Italy.

BMC CANCER, 2020; 20 (1):

Abstract

Background Colorectal cancer (CRC) is a heterogeneous disease with a complex biology and a wide number of altered genes such as BRAF, KRAS and PIK3CA.......

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