PKM2 ablation enhanced retinal function and survival in a preclinical model of retinitis pigmentosa

Zhang, E; Ryu, J; Levi, SR; Oh, JK; Hsu, CW; Cui, X; Lee, TT; Wang, NK; de Carvalho, JRL; Tsang, SH

Tsang, SH (corresponding author), New York Presbyterian Hosp, Jonas Childrens Vis Care & Bernard & Shirlee Brow, Edward S Harkness Eye Inst, New York, NY 10032 USA.; Tsang, SH (corresponding author), Columbia Univ, Inst Human Nutr, Dept Pathol & Cell Biol, New York, NY 10032 USA.; Tsang, SH (corresponding author), Columbia Univ, Columbia Stem Cell Initiat, New York, NY 10027 USA.

MAMMALIAN GENOME, 2020; 31 (3-4): 77

Abstract

Retinitis pigmentosa (RP) is a neurodegenerative disorder that causes irreversible vision loss in over 1.5 million individuals world-wide. The genetic......

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