Biophysical characterization of the interaction between the full-length XIAP and Smac/DIABLO

Polykretis, P; Luchinat, E

Polykretis, P (corresponding author), Univ Florence, CERM Magnet Resonance Ctr, Via Luigi Sacconi 6, I-50019 Florence, Italy.; Luchinat, E (corresponding author), Univ Florence, Neurofarba Dept, Via Ugo Schiff 6, I-50019 Sesto Fiorentino, Italy.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021; 568 (): 180

Abstract

XIAP is multi-functional protein which regulates apoptosis acting as a direct caspase inhibitor. It is overexpressed in cancer cells, where it antagon......

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