CD22 Promotes B-1b Cell Responses to T Cell-Independent Type 2 Antigens

Haas, KM; Johnson, KL; Phipps, JP; Do, C

Haas, KM (reprint author), Wake Forest Sch Med, Dept Microbiol & Immunol, 575 North Patterson Ave, Winston Salem, NC 27157 USA.

JOURNAL OF IMMUNOLOGY, 2018; 200 (5): 1671

Abstract

CD22 (Siglec-2) is a critical regulator of B cell activation and survival. CD22(-/-) mice generate significantly impaired Ab responses to T cell-indep......

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