Inhibiting autophagy with chloroquine enhances the anti-tumor effect of high-LET carbon ions via ER stress-related apoptosis

Zheng, XG; Jin, XD; Li, FF; Liu, XX; Liu, Y; Ye, F; Li, P; Zhao, T; Li, Q

Li, Q (reprint author), Chinese Acad Sci, Inst Modern Phys, 509 Nanchang Rd, Lanzhou 730000, Peoples R China.; Li, Q (reprint author), Chinese Acad Sci, Key Lab Heavy Ion Radiat Biol & Med, Lanzhou 730000, Peoples R China.; Li, Q (reprint author), Key Lab

MEDICAL ONCOLOGY, 2017; 34 (2):

Abstract

Energetic carbon ions (CI) offer great advantages over conventional radiations such as X-or c-rays in cancer radiotherapy. High linear energy transfer......

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