Establishment and characterization of immortalized human breast cancer cell lines from breast cancer patient-derived xenografts (PDX)

Zhuang, YX; Grainger, JM; Vedell, PT; Yu, J; Moyer, AM; Gao, HY; Fan, XY; Qin, SS; Liu, D; Kalari, KR; Goetz, MP; Boughey, JC; Weinshilboum, RM; Wang, LW

Wang, LW (corresponding author), Mayo Clin, Div Clin Pharmacol, Dept Mol Pharmacol & Expt Therapeut, Rochester, MN 55905 USA.

NPJ BREAST CANCER, 2021; 7 (1):

Abstract

The application of patient-derived xenografts (PDX) in drug screening and testing is a costly and time-consuming endeavor. While cell lines permit ext......

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