Targeting CDK4 and CDK6 in cancer

Goel, S; Bergholz, JS; Zhao, JJ

Goel, S (通讯作者),Peter MacCallum Canc Ctr, Melbourne, Vic, Australia.;Goel, S (通讯作者),Univ Melbourne, Sir Peter MacCallum Dept Oncol, Melbourne, Vic, Australia.;Zhao, JJ (通讯作者),Dana Farber Canc Inst, Boston, MA 02115 USA.;Zhao, JJ (通讯作者),Harvard Med Sch, Boston, MA 02115 USA.;Zhao, JJ (通讯作者),Broad Inst Harvard & MIT, Cambridge, MA 02142 USA.

NATURE REVIEWS CANCER, 2022; 22 (6): 356

Abstract

Dysregulation of cyclin-dependent kinase 4 (CDK4) and CDK6, regulators of the cell cycle, favours the growth and survival of several cancer types. Owi......

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