Examination of the Impact of CYP3A4/5 on Drug-Drug Interaction between Schizandrol A/Schizandrol B and Tacrolimus (FK-506): A Physiologically Based Pharmacokinetic Modeling Approach

He, QF; Bu, FJ; Wang, QZ; Li, M; Lin, JY; Tang, ZJ; Mak, WY; Zhuang, XM; Zhu, X; Lin, HS; Xiang, XQ

Xiang, XQ (通讯作者)，Fudan Univ, Sch Pharm, Dept Clin Pharm & Pharm Adm, Shanghai 201203, Peoples R China.;Lin, HS (通讯作者)，Shenzhen Technol Univ, Coll Pharm, Shenzhen 518118, Peoples R China.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022; 23 (9):

Abstract

Schizandrol A (SZA) and schizandrol B (SZB) are two active ingredients of Wuzhi capsule (WZC), a Chinese proprietary medicine commonly prescribed to a......

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