Targeting SYK signaling in myeloid cells protects against liver fibrosis and hepatocarcinogenesis

Torres-Hernandez, A; Wang, W; Nikiforov, Y; Tejada, K; Torres, L; Kalabin, A; Wu, Y; Ul Haq, MI; Khan, MY; Zhao, Z; Su, WY; Camargo, J; Hundeyin, M; Diskin, B; Adam, S; Rossi, JAK; Kurz, E; Aykut, B; Shadaloey, SAA; Leinwand, J; Miller, G

Miller, G (reprint author), NYU, Sch Med, Dept Surg, SA Localio Lab, 450 East 29th St, New York, NY 10016 USA.; Miller, G (reprint author), NYU, Sch Med, Dept Cell Biol, 450 East 29th St, New York, NY 10016 USA.

ONCOGENE, 2019; 38 (23): 4512

Abstract

Liver fibrosis and fibrosis-associated hepatocarcinogenesis are driven by chronic inflammation and are leading causes of morbidity and death worldwide......

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