Celastrol mediates Th17 and Treg cell generation via metabolic signaling

Zhang, JB; Shan, J; Chen, XL; Li, SF; Long, D; Li, YP

Li, YP (reprint author), Sichuan Univ, West China Hosp, Chengdu, Sichuan, Peoples R China.; Shan, J (reprint author), Chengdu Med Coll, Chengdu, Sichuan, Peoples R China.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018; 497 (3): 883

Abstract

A T helper 17 (Th17) cell/regulatory T (Treg) cell imbalance is involved in many immune disorders and diseases. Celastrol, a Chinese herbal compound t......

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