FTD-associated behavioural and transcriptomic abnormalities in 'humanized' progranulin-deficient mice: A novel model for progranulin-associated FTD

Life, B; Petkau, TL; Cruz, GNF; Navarro-Delgado, EI; Shen, N; Korthauer, K; Leavitt, BR

Leavitt, BR (通讯作者)，Univ British Columbia, Ctr Mol Med & Therapeut, Dept Med Genet, BC Childrens Hosp, 950 West 28th Ave, Vancouver, BC V5Z 4H4, Canada.

NEUROBIOLOGY OF DISEASE, 2023; 182 ():

Abstract

Frontotemporal dementia (FTD) is an early onset dementia characterized by neuropathology and behavioural changes. A common genetic cause of FTD is hap......

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