Combination of ion-pair strategy and chemical enhancers for design of dexmedetomidine long-acting patches: Dual action mechanism induced longer controlled release and better delivery efficiency

Sun, YT; Liu, C; Ren, SJ; Zhang, Y; Ruan, JH; Fang, L

Fang, L (通讯作者),Shenyang Pharmaceut Univ, Dept Pharmaceut Sci, 103 Wenhua Rd, Shenyang 110016, Liaoning, Peoples R China.

EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 2023; 183 (): 47

Abstract

The purpose of this study was to prepare a dexmedetomidine (Dex) 72 h long-acting patch by the combined use of ion-pair strategy and chemical enhancer......

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