Adenosine A(2A) receptor stimulation restores cell functions and differentiation in Niemann-Pick type C-like oligodendrocytes

De Nuccio, C; Bernardo, A; Ferrante, A; Pepponi, R; Martire, A; Falchi, M; Visentin, S; Popoli, P; Minghetti, L

De Nuccio, C (reprint author), Ist Super Sanita, Res Coordinat & Support Serv, Viale Regina Elena 299, I-00161 Rome, Italy.

SCIENTIFIC REPORTS, 2019; 9 ():

Abstract

Niemann Pick type C (NPC) disease is a rare neurovisceral disorder. Mutations in npc1 gene induce an intracellular accumulation of unesterified choles......

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