Mutations inhibiting KDM4B drive ALT activation in ATRX-mutated glioblastomas

Udugama, M; Hii, L; Garvie, A; Cervini, M; Vinod, B; Chan, FL; Das, PP; Mann, JR; Collas, P; Voon, HPJ; Wong, LH

Voon, HPJ; Wong, LH (corresponding author), Monash Univ, Biomed Discovery Inst, Dept Biochem & Mol Biol, Clayton, Vic, Australia.

NATURE COMMUNICATIONS, 2021; 12 (1):

Abstract

Alternative Lengthening of Telomeres (ALT) is a telomere maintenance pathway utilised in 15% of cancers that have been associated with mutations in AT......

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