The Synergistic Anti-Tumor Activity of EZH2 Inhibitor SHR2554 and HDAC Inhibitor Chidamide through ORC1 Reduction of DNA Replication Process in Diffuse Large B Cell Lymphoma

Wang, X; Wang, DD; Ding, N; Mi, L; Yu, H; Wu, M; Feng, F; Hu, LN; Zhang, YM; Zhong, C; Ye, YY; Li, J; Fang, W; Shi, YF; Deng, LJ; Ying, ZT; Song, YQ; Zhu, J

Song, YQ; Zhu, J (corresponding author), Peking Univ Canc Hosp & Inst, Dept Lymphoma, Key Lab Carcinogenesis & Translat Res, Minist Educ, 52 Fucheng Rd, Beijing 100142, Peoples R China.

CANCERS, 2021; 13 (17):

Abstract

Simple Summary The EZH2-targeted drugs have demonstrated notable therapeutic effects in EZH2 mutant B-cell lymphoma patients. In this study, we demons......

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