PHF19 activates hedgehog signaling and promotes tumorigenesis in hepatocellular carcinoma

Shi, XY; Zi, YY; Xing, J; Nie, YJ; Xie, Q; Deng, YZ; Xin, HG

Deng, YZ (corresponding author), Cent South Univ, Xiangya Hosp, Xiangya Canc Ctr, Changsha 410008, Peoples R China.; Xin, HG (corresponding author), Shanghai Jiao Tong Univ, Sch Med, Ruijin Hosp, Dept Infect Dis, Shanghai 200025, Peoples R China.

EXPERIMENTAL CELL RESEARCH, 2021; 406 (1):

Abstract

Aberrant activation of Hedgehog-Gli1 signaling and accumulation of Gli1 in hepatocellular carcinoma (HCC) are frequently observed. However, the mechan......

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