Novel Bruton's tyrosine kinase inhibitor remibrutinib: Assessment of drug-drug interaction potential as a perpetrator of cytochrome P450 enzymes and drug transporters and the impact of covalent binding on possible drug interactions

Schiller, H; Huth, F; Schuhler, C; Drollmann, A; Kaul, M; Woessner, R; Shah, BR; Weis, W; End, P

End, P (通讯作者),Novartis Inst BioMed Res, Basel, Switzerland.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2022; 172 ():

Abstract

Purpose: Pharmacokinetic drug-drug interactions (DDIs) are investigated to ensure safety for patients receiving concomitant medications. Here, we pres......

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