Microtubule acetylation induced by oxidative stress regulates subcellular distribution of lysosomal vesicles for amyloid-beta secretion

Jeong, J; Kim, OH; Shim, J; Keum, S; Hwang, YE; Song, SE; Kim, JW; Choi, JH; Lee, HJ; Rhee, S

Choi, JH; Rhee, S (通讯作者)，Chung Ang Univ, Dept Life Sci, Seoul 06974, South Korea.;Lee, HJ (通讯作者)，Chung Ang Univ, Coll Med, Dept Anat & Cell Biol, Seoul 06974, South Korea.

JOURNAL OF CELLULAR PHYSIOLOGY, 2023; 238 (12): 2812

Abstract

Excessive production and accumulation of amyloid-beta (A beta) in the brain are one of the hallmarks of Alzheimer's disease (AD). Although oxidative s......

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