Targeting EGFR(L858R/T790M) and EGFR(L858R/T790M/C797S) resistance mutations in NSCLC: Current developments in medicinal chemistry

Lu, XY; Yu, L; Zhang, Z; Ren, XM; Smaill, JB; Ding, K

Lu, XY; Ding, K (reprint author), Jinan Univ, Sch Pharm, 601 Huangpu Ave West, Guangzhou 510632, Guangdong, Peoples R China.

MEDICINAL RESEARCH REVIEWS, 2018; 38 (5): 1550

Abstract

Both the first-generation reversible epidermal growth factor receptor (EGFR) inhibitors gefitinib and erlotinib and the second-generation covalent epi......

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