Pharmacological inhibition of NF-kappa B-inducing kinase (NIK) with small molecules for the treatment of human diseases

Cheng, J; Feng, XX; Li, ZQ; Zhou, FL; Yang, JM; Zhao, YJ

Zhao, YJ (corresponding author), Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China.; Zhao, YJ (corresponding author), Univ Chinese Acad Sci, Beijing 100049, Peoples R China.; Zhao, YJ (corresponding author), Zhengzhou Univ, Sch Pharmaceut Sci, Zhengzhou 450001, Peoples R China.

RSC MEDICINAL CHEMISTRY, 2021; 12 (4): 552

Abstract

NIK is a key kinase required for the activation of alternative NF-kappa B signaling pathways. Overactivation of NIK in patients has been observed and ......

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