Safety, tolerability, pharmacokinetics, and pharmacodynamics of a TLR7 agonist prodrug RO6870868 in healthy volunteers

Grippo, JF; Folitar, I; Passe, S; Jiang, QD; Rodriguez, I; Fettner, SH; Calleja, E

Grippo, JF (corresponding author), Deep Dives Pharma Res LLC, 28 Spruce St, Basking Ridge, NJ 07920 USA.

CTS-CLINICAL AND TRANSLATIONAL SCIENCE, 2021; 14 (4): 1524

Abstract

RO6870868 is an oral prodrug of the toll-like receptor 7 (TLR7) specific agonist, RO6871765. TLR7 agonists augment host immune activity and are in dev......

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