Discovery of selective BPTF bromodomain inhibitors by screening and structure-based optimization

Xiong, L; Mao, X; Guo, YP; Zhou, YL; Chen, MX; Chen, P; Yang, SY; Li, LL

Li, LL (corresponding author), Sichuan Univ, West China Sch Pharm, Minist Educ, Key Lab Drug Targeting & Drug Delivery Syst, Chengdu 610041, Sichuan, Peoples R China.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021; 545 (): 125

Abstract

Bromodomain and PHD finger containing transcription factor (BPTF) is a multidomain protein that regulates the transcription of chromatin and is relate......

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