Identification of ryuvidine as a KDM5A inhibitor

Mitsui, E; Yoshida, S; Shinoda, Y; Matsumori, Y; Tsujii, H; Tsuchida, M; Wada, S; Hasegawa, M; Ito, A; Mino, K; Onuki, T; Yoshida, M; Sasaki, R; Mizukami, T

Mizukami, T (reprint author), Nagahama Inst Biosci & Tech, 1266 Tamura, Nagahama, Shiga 5260829, Japan.; Mizukami, T (reprint author), Frontier Pharma Inc, 1281-8 Tamura, Nagahama, Shiga 5260829, Japan.

SCIENTIFIC REPORTS, 2019; 9 ():

Abstract

KDM5 family members (A, B, C and D) that demethylate H3K4me3 have been shown to be involved in human cancers. Here we performed screening for KDM5A in......

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