Overexpression of bHLH domain of HIF-1 failed to inhibit the HIF-1 transcriptional activity in hypoxia

Sadeghi, F; Kardar, GA; Bolouri, MR; Nasri, F; Sadri, M; Falak, R

Falak, R (corresponding author), Iran Univ Med Sci, Sch Med, Dept Immunol, Tehran, Iran.; Kardar, GA (corresponding author), Univ Tehran Med Sci, Childrens Med Ctr, Immunol Asthma & Allergy Res Inst, Tehran, Iran.

BIOLOGICAL RESEARCH, 2020; 53 (1):

Abstract

Background Hypoxia inducible factor-1 (HIF-1) is considered as the most activated transcriptional factor in response to low oxygen level or hypoxia. H......

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