mTOR Signaling Upregulates CDC6 via Suppressing miR-3178 and Promotes the Loading of DNA Replication Helicase

Wu, XJ; Li, SH; Hu, X; Xiang, XL; Halloran, M; Yang, LL; Williams, TM; Houghton, PJ; Shen, CX; He, ZF

Shen, CX (reprint author), Ohio State Univ, Ctr Comprehens Canc, Columbus, OH 43210 USA.; He, ZF (reprint author), Zhejiang Univ, Dept Thorac Surg, Coll Med, Sir Run Run Shaw Hosp, Hangzhou 310016, Zhejiang, Peoples R China.

SCIENTIFIC REPORTS, 2019; 9 ():

Abstract

mTOR signaling pathway is deregulated in most cancers and uncontrolled cell cycle progression is a hallmark of cancer cell. However, the precise molec......

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