Human Carboxylesterase 1A Plays a Predominant Role in Hydrolysis of the Anti-Dyslipidemia Agent Fenofibrate in Humans

Li, HX; Sun, MR; Zhang, Y; Song, LL; Zhang, F; Song, YQ; Hou, XD; Ge, GB

Ge, GB (通讯作者)，Shanghai Univ Tradit Chinese Med, Inst Interdisciplinary Integrat Med Res, Shanghai Frontiers Sci Ctr TCM Chem Biol, Shanghai, Peoples R China.;Ge, GB (通讯作者)，Shanghai Univ Tradit Chinese Med, Inst Interdisciplinary Integrat, Med Res, Shanghai 201203, Peoples R China.

DRUG METABOLISM AND DISPOSITION, 2023; 51 (11): 1490

Abstract

Fenofibrate, a marketed peroxisome proliferator-activated receptor-alpha (PPAR alpha) agonist, has been widely used for treating severe hypertriglycer......

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