BET inhibitors RVX-208 and PFI-1 reactivate HIV-1 from latency

Lu, PP; Shen, YZ; Yang, H; Wang, YN; Jiang, ZT; Yang, XY; Zhong, YC; Pan, HY; Xu, JQ; Lu, HZ; Zhu, HZ

Zhu, HZ (reprint author), Fudan Univ, Inst Genet, Sch Life Sci, State Key Lab Genet Engn, Shanghai 200438, Peoples R China.

SCIENTIFIC REPORTS, 2017; 7 ( ):

Abstract

Persistent latent reservoir in resting CD4+T cells is a major obstacle in curing HIV-1 infection. Effective strategies for eradication of the HIV-1 re......

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