Exaggerated activities of TRPM7 underlie bupivacaine-induced neurotoxicity in the SH-SY5Y cells preconditioned with high glucose

Dai, SH; Li, YW; Hong, QX; Su, T; Xu, SY

Xu, SY (corresponding author), Southern Med Univ, Dept Anesthesiol, Zhujiang Hosp, 253 Gongye Ave, Guangzhou 510282, Guangdong, Peoples R China.; Su, T (corresponding author), Guangzhou Med Univ, Affiliated Hosp 2, Inst Neurosci, Chang Gang Dong Rd 250, Guangzhou 510260, Guangdong, Peoples R China.

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 2021; 35 (8):

Abstract

Hyperglycemia is considered a risk factor for the enhancement of local anesthetic-induced neurotoxicity. Transient receptor potential melastatin 7 (TR......

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