Acetyl-CoA synthetase 2 promotes diabetic renal tubular injury in mice by rewiring fatty acid metabolism through SIRT1/ChREBP pathway

Lu, J; Li, XQ; Chen, PP; Zhang, JX; Li, L; Wang, GH; Liu, XQ; Jiang, CM; Ma, KL

Jiang, CM (通讯作者)，Nanjing Univ, Nanjing Drum Tower Hosp, Dept Nephrol, Affiliated Hosp,Med Sch, Nanjing 210008, Peoples R China.;Ma, KL (通讯作者)，Zhejiang Univ, Affiliated Hosp 2, Sch Med, Dept Nephrol, Hangzhou 310003, Peoples R China.

ACTA PHARMACOLOGICA SINICA, 2023; ():

Abstract

Diabetic nephropathy (DN) is characterized by chronic low-grade renal inflammatory responses, which greatly contribute to disease progression. Abnorma......

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