The aptamer BT200 effectively inhibits von Willebrand factor (VWF) dependent platelet function after stimulated VWF release by desmopressin or endotoxin

Kovacevic, KD; Buchtele, N; Schoergenhofer, C; Derhaschnig, U; Gelbenegger, G; Brostjan, C; Zhu, SH; Gilbert, JC; Jilma, B

Jilma, B (corresponding author), Med Univ Vienna, Dept Clin Pharmacol, Wahringer Gurtel 18-20, A-1090 Vienna, Austria.

SCIENTIFIC REPORTS, 2020; 10 (1):

Abstract

Von Willebrand factor (VWF) plays a major role in arterial thrombosis. Antiplatelet drugs induce only a moderate relative risk reduction after atherot......

Full Text Link


Links

期刊讨论 | 中国SCI论文 | 期刊主页 | 投稿经验 | 杂志官网 | 投稿链接 | 作者需知 | PMC链接 | Pubmed全文检索