Synergistic effect of the inhibitors of RAF/MEK and AXL on KRAS-mutated ovarian cancer cells with high AXL expression

Umemura, S; Sowa, Y; Iizumi, Y; Kitawaki, J; Sakai, T

Sowa, Y (corresponding author), Kyoto Prefectural Univ Med, Grad Sch Med Sci, Dept Mol Targeting Prevent, Kamikyo Ku, Kawaramachi Hirokoji, Kyoto, Japan.

CANCER SCIENCE, 2020; 111 (6): 2052

Abstract

KRAS mutation is frequently seen in a subtype of ovarian cancer categorized as type 1. The KRAS-MAPK pathway, which is closely involved in type 1 canc......

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