An onboard checking mechanism ensures effector delivery of the type VI secretion system in Vibrio cholerae

Liang, XY; Kamal, F; Pei, TT; Xu, P; Mekalanos, JJ; Dong, TG

Dong, TG (reprint author), Shanghai Jiao Tong Univ, Sch Life Sci & Biotechnol, Joint Int Lab Metab & Dev Sci, State Key Lab Microbial Metab, Shanghai 200240, Peoples R China.; Dong, TG (reprint author), Univ Calgary, Dept Ecosyst & Publ Hlth, Calgary, AB

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2019; 116 (46): 23292

Abstract

The type VI secretion system (T6SS) is a lethal yet energetically costly weapon in gram-negative bacteria. Through contraction of a long sheath, the T......

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