Targeting FcRn for immunomodulation: Benefits, risks, and practical considerations

Peter, HH; Ochs, HD; Cunningham-Rundles, C; Vinh, DC; Kiessling, P; Greve, B; Jolles, S

Jolles, S (corresponding author), Univ Hosp Wales, Immunodeficiency Ctr Wales, Cardiff CF14 4XW, Wales.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2020; 146 (3): 479

Abstract

The neonatal fragment crystallizable (Fc) receptor (FcRn) functions as a recycling mechanism to prevent degradation and extend the half-life of IgG an......

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