Oncogenic AKTivation by methylation

Luciano, AK; Guertin, DA

Guertin, DA (reprint author), Univ Massachusetts, Program Mol Med, Sch Med, Worcester, MA 01655 USA.; Guertin, DA (reprint author), Univ Massachusetts, Dept Mol Cell & Canc Biol, Sch Med, Worcester, MA 01655 USA.

NATURE CELL BIOLOGY, 2019; 21 (2): 114

Abstract

AKT, also known as protein kinase B, is one of the most frequently dysregulated serine/threonine kinases in cancer, and its hyperactivity drives tumor......

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