Saturated fatty acids entrap PDX1 in stress granules and impede islet beta cell function

Zhang, M; Yang, CJ; Zhu, M; Qian, L; Luo, Y; Cheng, HM; Geng, R; Xu, XJ; Qian, C; Liu, Y

Xu, XJ; Liu, Y (corresponding author), Nanjing Med Univ, Sir Run Run Hosp, Dept Endocrinol, Nanjing, Peoples R China.; Qian, C (corresponding author), Nanjing Med Univ, Sir Run Run Hosp, Dept Nephrol, Nanjing, Peoples R China.

DIABETOLOGIA, ; ():

Abstract

Aims/hypothesis Failure of pancreatic and duodenal homeobox factor 1 (PDX1) to localise in the nucleus of islet beta cells under high-fat diet (HFD) c......

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