AMG-510 and cisplatin combination increases antitumor effect in lung adenocarcinoma with mutation of KRAS G12C: a preclinical and translational research

Wu, LL; Jiang, WM; Liu, ZY; Zhang, YY; Qian, JY; Liu, YE; Huang, YY; Li, K; Li, ZX; Ma, GW; Xie, D

Xie, D (通讯作者),Tongji Univ, Shanghai Pulm Hosp, Sch Med, Dept Thorac Surg, Shanghai 200433, Peoples R China.;Ma, GW (通讯作者),Sun Yat sen Univ, Collaborat Innovat Ctr Canc Med, Canc Ctr, State Key Lab Oncol South China, Guangzhou 510030, Peoples R China.

DISCOVER ONCOLOGY, 2023; 14 (1):

Abstract

BackgroundThe efficacy of monotherapy of AMG-510 is limited. This study explored whether the AMG-510 and cisplatin combination increases the anti-tumo......

Full Text Link