Brown adipose tissue involution associated with progressive restriction in progenitor competence

Huang, Z; Zhang, ZD; Moazzami, Z; Heck, R; Hu, P; Nanda, H; Ren, KQ; Sun, ZQ; Bartolomucci, A; Gao, Y; Chung, DJ; Zhu, WY; Shen, S; Ruan, HB

Huang, Z (通讯作者)，Nanjing Agr Univ, Coll Anim Sci & Technol, Lab Gastrointestinal Microbiol, Jiangsu Key Lab Gastrointestinal Nutr & Anim Hlth, Nanjing 210095, Jiangsu, Peoples R China.;Huang, Z (通讯作者)，Nanjing Agr Univ, Natl Ctr Int Res Anim Gut Nutr, Nanjing 210095, Jiangsu, Peoples R China.;Huang, Z; Ruan, HB (通讯作者)，Univ Minnesota, Dept Integrat Biol & Physiol, Sch Med, Minneapolis, MN 55455 USA.;Ruan, HB (通讯作者)，Univ Minnesota, Ctr Immunol, Sch Med, Minneapolis, MN 55455 USA.

CELL REPORTS, 2022; 39 (2):

Abstract

Human brown adipose tissue (BAT) undergoes progressive involution. This involution process is not recapitulated in rodents, and the underlying mechani......

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