Synthesis and Evaluation of Acylated Derivatives of Hederagenin as Inhibitors of HIV-1 and HCV NS3/4A Proteases

Liu, Q; Wei, Y; Hao, YJ; Yang, J; Pan, BW; Yang, XS; Zhou, Y; Wang, X

Wei, Y (通讯作者),Guizhou Univ Tradit Chinese Med, Dept Pharm, South Dongqing Rd, Guiyang 550025, Guizhou, Peoples R China.;Yang, J (通讯作者),Univ Saskatchewan, Coll Pharm & Nutr, 107 Wiggins Rd, Saskatoon, SK S7N 5E5, Canada.

NATURAL PRODUCT COMMUNICATIONS, 2022; 17 (1):

Abstract

Viral infection imposes a major threat to human health. To develop new potent antiviral agents, Hederagenin (HE), a known inhibitor of HIV-1 and HCV N......

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