Depletion of DNA damage binding protein 2 sensitizes triple-negative breast cancer cells to poly ADP-ribose polymerase inhibition by destabilizing Rad51-MedSci.cn

Depletion of DNA damage binding protein 2 sensitizes triple-negative breast cancer cells to poly ADP-ribose polymerase inhibition by destabilizing Rad51

Zhao, L; Si, CS; Yu, Y; Lu, JW; Zhuang, Y

Zhuang, Y (reprint author), Nanjing Med Univ, Jiangsu Canc Hosp, Jiangsu Inst Canc Res, Dept Med Oncol,Affiliated Canc Hosp, Nanjing, Jiangsu, Peoples R China.

CANCER SCIENCE, 2019; 110 (11): 3543

Abstract

Poly ADP-ribose polymerase inhibitors (PARPi) have shown promising therapeutic efficacy in triple-negative breast cancer (TNBC) patients. However, res......

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