A40p53 isoform up-regulates netrin-1/UNC5B expression and potentiates netrin-1 pro-oncogenic activity

Sun, Y; Manceau, A; Frydman, L; Cappuccio, L; Neves, D; Basso, V; Wang, H; Fombonne, J; Maisse, C; Mehlen, P; Paradisi, A

Mehlen, P; Paradisi, A (corresponding author), Univ Claude Bernard Lyon1, Univ Lyon, Ctr Rech Cancerol Lyon,Equipe Labellisee Ligue,La, Ctr Leon Berard,INSERM U1052,CNRS UMR5286,Apoptos, F-69008 Lyon, France.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021; 118 (36):

Abstract

Netrin-1, a secreted protein recently characterized as a relevant cancer therapeutic target, is the antiapoptotic ligand of the dependence receptors d......

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