AKTivation mechanisms

Cole, PA; Chu, N; Salguero, AL; Bae, H

Cole, PA (reprint author), Brigham & Womens Hosp, Dept Med, Div Genet, 75 Francis St, Boston, MA 02115 USA.; Cole, PA (reprint author), Harvard Med Sch, Dept Biol Chem & Mol Pharmacol, Boston, MA 02115 USA.

CURRENT OPINION IN STRUCTURAL BIOLOGY, 2019; 59 (): 47

Abstract

Akt1-3 (Akt) are a subset of the AGC protein Ser/Thr kinase family and play important roles in cell growth, metabolic regulation, cancer, and other di......

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