Cholecystectomy promotes colon carcinogenesis by activating the Wnt signaling pathway by increasing the deoxycholic acid level

Yao, YX; Li, XJ; Xu, BH; Luo, L; Guo, QD; Wang, XY; Sun, L; Zhang, Z; Li, P

Zhang, Z; Li, P (通讯作者),Capital Med Univ, Beijing Friendship Hosp, Natl Clin Res Ctr Digest Dis,Dept Gastroenterol, Beijing Digest Dis Ctr,Beijing Key Lab Precanc Le, Beijing 100050, Peoples R China.;Sun, L (通讯作者),Natl Innovat Inst Def Technol, Innovat Lab Terahertz Biophys, Beijing 100071, Peoples R China.

CELL COMMUNICATION AND SIGNALING, 2022; 20 (1):

Abstract

Purpose: Cholecystectomy (XGB) is widely recognized as a risk factor for colon cancer (CC). Continuous exposure of the colonic epithelium to deoxychol......

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