Selective modifications of lactose and N-acetyllactosamine with sulfate and aromatic bulky groups unveil unique structural insights in galectin-1-ligand recognition

Massaro, M; Cagnoni, AJ; Medrano, FJ; Pérez-Sáez, JM; Abdullayev, S; Belkhadem, K; Mariño, K; Romero, A; Roy, R; Rabinovich, GA

Romero, A (通讯作者)，CSIC, Ctr Invest Biol Margarita Salas CIB, E-28040 Madrid, Spain.;Roy, R (通讯作者)，Univ Quebec Montreal, Glycosci & Nanomat Lab, Succ Ctr Ville,POB 8888, Montreal, PQ H3C 3P8, Canada.;Rabinovich, GA (通讯作者)，Consejo Nacl Invest Cient & Tecn CONICET, Lab Glicomed, Inst Biol & Med Expt IBYME, C1428, Buenos Aires, Argentina.

BIOORGANIC & MEDICINAL CHEMISTRY, 2023; 94 ():

Abstract

Galectins, a family of endogenous glycan-binding proteins, play crucial roles in a broad range of physiological and pathological processes. Galectin-1......

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