Linear ubiquitination induces NEMO phase separation to activate NF-KB signaling

Goel, S; Oliva, R; Jeganathan, S; Bader, V; Krause, LJ; Kriegler, S; Stender, ID; Christine, CW; Nakamura, K; Hoffmann, JE; Winter, R; Tatzelt, J; Winklhofer, KF

Winklhofer, KF (通讯作者)，Ruhr Univ Bochum, Inst Biochem & Pathobiochem, Dept Mol Cell Biol, Bochum, Germany.;Tatzelt, J; Winklhofer, KF (通讯作者)，Ruhr Univ Bochum, RESOLV Cluster Excellence, Bochum, Germany.;Tatzelt, J (通讯作者)，Ruhr Univ Bochum, Inst Biochem & Pathobiochem, Dept Biochem Neurodegenerat Dis, Bochum, Germany.

LIFE SCIENCE ALLIANCE, 2023; 6 (4):

Abstract

The NF-KB essential modulator NEMO is the core regulatory com-ponent of the inhibitor of KB kinase complex, which is a critical checkpoint in canonica......

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