Genetic loss of AMPK-glycogen binding destabilises AMPK and disrupts metabolism

Hoffman, NJ; Whitfield, J; Janzen, NR; Belhaj, MR; Galic, S; Murray-Segal, L; Smiles, WJ; Ling, NXY; Dite, TA; Scott, JW; Oakhill, JS; Brink, R; Kemp, BE; Hawley, JA

Hoffman, NJ; Hawley, JA (corresponding author), Australian Catholic Univ, Mary MacKillop Inst Hlth Res, Exercise & Nutr Res Program, Level 5,215 Spring St, Melbourne, Vic 3000, Australia.; Kemp, BE (corresponding author), Univ Melbourne, St Vincents Inst Med Res, 9 Princes St, Fitzroy, Vic 3065, Australia.; Kemp, BE (corresponding author), Univ Melbourne, Dept Med, 9 Princes St, Fitzroy, Vic 3065, Australia.

MOLECULAR METABOLISM, 2020; 41 ():

Abstract

Objective: Glycogen is a major energy reserve in liver and skeletal muscle. The master metabolic regulator AMP-activated protein kinase (AMPK) associa......

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