Palmitoylation of Ca2+ channel subunit Ca-V beta(2a) induces pancreatic beta-cell toxicity via Ca2+ overload

Kazim, AS; Storm, P; Zhang, EM; Renstrom, E

Zhang, EM; Renstrom, E (reprint author), Lund Univ, Lund Univ Diabet Ctr, Dept Clin Sci Malmo, SE-20502 Malmo, Sweden.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2017; 491 (3): 740

Abstract

High blood glucose triggers the release of insulin from pancreatic beta cells, but if chronic, causes cellular stress, partly due to impaired Ca2+ hom......

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