Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains

Yuan, Y; Cao, DF; Zhang, YF; Ma, J; Qi, JX; Wang, QH; Lu, GW; Wu, Y; Yan, JH; Shi, Y; Zhang, XZ; Gao, GF

Gao, GF (reprint author), Univ Sci & Technol China, Sch Life Sci, Hefei 230026, Anhui, Peoples R China.; Shi, Y; Gao, GF (reprint author), Chinese Acad Sci, Inst Microbiol, CAS Key Lab Pathogen Microbiol & Immunol, Beijing 100101, Peoples R China.; Zhang,

NATURE COMMUNICATIONS, 2017; 8 ( ):

Abstract

The envelope spike (S) proteins of MERS-CoV and SARS-CoV determine the virus host tropism and entry into host cells, and constitute a promising target......

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