H1, a derivative of tetrandrine, enhances the efficacy of 5-FU in Bel7402/5-FU cells via suppressing STAT3/MCL-1 and inducing PUMA

Li, FL; Wang, J; Wu, N; Zhang, H; Li, Z; Wei, N

Wang, J (reprint author), Jinzhou Med Univ, Affiliated Hosp 1, Jinzhou, Peoples R China.; Wei, N (reprint author), Univ Pittsburgh, Sch Med, Div Hematol Oncol, Pittsburgh, PA 15232 USA.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2019; 520 (1): 93

Abstract

Currently, 5-fluorouracil (5-FU) resistance became a major obstacle to its clinical use for patients with hepatocellular carcinoma (HCC). It's urgent ......

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